TNF alpha antibody

Catalog No. ABIN1967143

This Mouse Monoclonal antibody specifically detects TNF alpha in WB, ELISA, Neut, Func and BR. It exhibits reactivity toward Human.

Quick Overview for TNF alpha antibody (ABIN1967143)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Neutralization (Neut), Functional Studies (Func), Blocking Reagent (BR)

Clone: MAb1

Product Details anti-TNF alpha Antibody

Specificity: Monoclonal antibody MAb1 recognizes human 17-26 kD cytokine TNF-alpha (tumor necrosis factor alpha).

Purification: Protein A purified

Sterility: Sterile filtered

Immunogen: Recombinant human TNF-alpha.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: Block, ELISA, Func, Neut, WB

Usage: ELISA: Application note - Can be used as capture antibody in combination with biotinylated antibody MAb11. Functional Application: neutralization. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, sterile filtered.

Preservative: Azide free

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF Alpha

Background: Name/Gene ID: TNF
Family: TNF

Synonyms: TNF, APC1 protein, Cachectin, DIF, TNF Alpha, Tumor necrosis factor-alpha, TNF-alpha, TNF-a, TNFA, Tumor necrosis factor, TNF, macrophage-derived, TNF, monocyte-derived, TNFSF2

Gene ID: 7124

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome